Once Human is a multiplayer open-world survival game set in a post-apocalyptic world where humanity battles terrifying supernatural entities. Developed by Starry Studio, the game is scheduled for release on mobile devices on April 23, 2025. It plunges players into a mysterious and hazardous landscape teeming with mutated creatures, bizarre anomalies, and formidable foes. To withstand these threats, you must equip a variety of powerful weapons. This tier list ranks the top weapons for all PvE modes in the game. Explore our rankings below!

The DB12 – Backfire is an epic-grade shotgun. It boasts a base damage of 49×5, a fire rate of 105, and a magazine capacity of 12. Its unique "Frost Vortex" ability creates a 4.5-meter area-of-effect zone that traps enemies, dealing 30% Psi Intensity status damage per second for 4 seconds. The weapon also features multiple passive abilities that activate under specific conditions:
Landing 5 hits on an enemy triggers the Frost Vortex.After striking enemies within the Frost Vortex once, they become Frozen for 3 seconds (4-second cooldown; cannot be refrozen during this period).Attacks against Frozen enemies deal +60% extra damage.
Players can also experience Once Human on a larger screen using BlueStacks on their PC or laptop, benefiting from keyboard and mouse controls.